Motif ID: DMAP1_NCOR{1,2}_SMARC.p2

Z-value: 1.103


Transcription factors associated with DMAP1_NCOR{1,2}_SMARC.p2:

Gene SymbolEntrez IDGene Name
DMAP1 55929 DNA methyltransferase 1 associated protein 1
NCOR1 9611 nuclear receptor co-repressor 1
NCOR2 9612 nuclear receptor co-repressor 2
SMARCA1 6594 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA5 8467 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC2 6601 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SMARCC2hg19_v1_chr12_-_56583301_565833940.609.7e-09Click!
DMAP1hg19_v1_chr1_+_44679111_446791750.412.4e-04Click!
NCOR1hg19_v1_chr17_-_16097882_160979550.352.1e-03Click!
NCOR2hg19_v1_chr12_-_125052009_125052141-0.317.2e-03Click!
SMARCA1hg19_v1_chrX_-_128657381_1286574360.113.4e-01Click!
SMARCA5hg19_v1_chr4_+_144434555_144434902-0.066.0e-01Click!


Activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2.

activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2


Sorted Z-values histogram for motif DMAP1_NCOR{1,2}_SMARC.p2

Sorted Z-values for motif DMAP1_NCOR{1,2}_SMARC.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DMAP1_NCOR{1,2}_SMARC.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_137475076 8.890 NM_003551
NME5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr3_-_9291251 7.580 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr16_+_4838397 7.509 NM_001253790
NM_001253791
LOC440335

uncharacterized LOC440335

chr11_+_34654010 6.070 NM_001206616
EHF
ets homologous factor
chr12_+_54447660 5.951 NM_153633
HOXC4
HOXC6
homeobox C4
homeobox C6
chr6_+_31913708 5.644 NM_001710
CFB
complement factor B
chr17_-_40264687 5.587 NM_024119
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr5_-_154230157 5.537 C5orf4
chromosome 5 open reading frame 4
chr5_-_154230212 5.357 NM_032385
C5orf4
chromosome 5 open reading frame 4
chr9_-_14086901 5.129 NFIB
nuclear factor I/B
chr5_+_42565963 4.925 NM_001242460
NM_001242461
NM_001242462
GHR


growth hormone receptor


chr8_-_108510094 4.809 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr6_+_31913763 4.736 CFB
complement factor B
chr6_+_31913852 4.650 CFB
complement factor B
chr15_+_45028559 4.290 NM_080745
NM_182985
TRIM69

tripartite motif containing 69

chr2_-_216246961 4.161 FN1
fibronectin 1
chr7_-_92777657 4.093 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr5_-_154230148 3.969 C5orf4
chromosome 5 open reading frame 4
chr11_-_18258383 3.943 NM_006512
SAA4
serum amyloid A4, constitutive
chr1_-_150738292 3.921 NM_001199739
NM_004079
CTSS

cathepsin S

chr18_+_21452981 3.833 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr4_-_169239816 3.739 NM_017631
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr5_+_133842276 3.691


chr14_+_64680858 3.674 NM_182913
SYNE2
spectrin repeat containing, nuclear envelope 2
chr20_+_44746889 3.673 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr4_-_186733372 3.586 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr6_-_48078909 3.549 C6orf138
chromosome 6 open reading frame 138
chr6_+_31913920 3.495 CFB
complement factor B
chr10_+_91061705 3.441 NM_001547
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr20_+_44746948 3.410 CD40
CD40 molecule, TNF receptor superfamily member 5
chr2_-_157189040 3.384 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr12_-_10324675 3.200 NM_001172632
NM_001172633
NM_002543
OLR1


oxidized low density lipoprotein (lectin-like) receptor 1


chr1_-_12677347 3.180 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr2_+_210444154 3.129 MAP2
microtubule-associated protein 2
chr8_+_17396285 3.127 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr17_-_67138013 3.071 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr12_-_62586547 3.023 NM_178539
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr12_-_49318663 3.016 NM_001143781
FKBP11
FK506 binding protein 11, 19 kDa
chr21_-_31588242 2.882 NM_199328
CLDN8
claudin 8
chr5_-_138775138 2.871 DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr10_+_91152321 2.844 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr5_+_42565562 2.838 NM_001242406
GHR
growth hormone receptor
chr4_+_87968191 2.822 AFF1
AF4/FMR2 family, member 1
chr14_-_89878733 2.764 FOXN3
forkhead box N3
chr15_+_48010685 2.736 NM_020858
NM_024966
NM_153616
NM_153617
NM_153618
NM_153619
SEMA6D





sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D





chr1_-_150738232 2.729 CTSS
cathepsin S
chr2_-_216242916 2.704 FN1
fibronectin 1
chr12_-_15865847 2.674 EPS8
epidermal growth factor receptor pathway substrate 8
chr3_-_49851217 2.647 UBA7
ubiquitin-like modifier activating enzyme 7
chr1_+_154298026 2.638 ATP8B2
ATPase, class I, type 8B, member 2
chr5_-_42811959 2.625 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr11_-_104916041 2.601 NM_001017534
NM_052889
CARD16

caspase recruitment domain family, member 16

chr4_-_186732208 2.597 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr1_-_150738255 2.594 CTSS
cathepsin S
chr4_-_122085475 2.560 NM_024873
TNIP3
TNFAIP3 interacting protein 3
chr10_+_74870209 2.535 NM_015901
NUDT13
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr9_-_73029539 2.515 NM_001206
KLF9
Kruppel-like factor 9
chr12_-_7245006 2.466 NM_001733
C1R
complement component 1, r subcomponent
chr17_+_48545689 2.441 ACSF2
acyl-CoA synthetase family member 2
chrX_+_105412297 2.393 NM_001171020
NM_152423
MUM1L1

melanoma associated antigen (mutated) 1-like 1

chrX_+_105937067 2.387 NM_024539
RNF128
ring finger protein 128
chr12_-_56359794 2.383 NM_001200053
NM_001200054
PMEL

premelanosome protein

chr11_-_8680382 2.358 NM_014818
TRIM66
tripartite motif containing 66
chr1_+_149754245 2.347 NM_000566
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr14_-_107218786 2.318 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr11_+_109963524 2.313 ZC3H12C
zinc finger CCCH-type containing 12C
chr10_+_91092238 2.299 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr4_-_39640461 2.285 NM_174921
C4orf34
chromosome 4 open reading frame 34
chr8_-_145060563 2.280 PARP10
poly (ADP-ribose) polymerase family, member 10
chr4_+_113218498 2.278 NM_001102406
NM_025144
ALPK1

alpha-kinase 1

chr3_+_69812961 2.269 NM_006722
MITF
microphthalmia-associated transcription factor
chr7_+_100136845 2.264 AGFG2
ArfGAP with FG repeats 2
chr19_-_44384240 2.261 NM_001033719
ZNF404
zinc finger protein 404
chr5_-_138775213 2.246 NM_152686
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr5_+_162887516 2.239 NM_001142556
NM_001142557
NM_012484
NM_012485
HMMR



hyaluronan-mediated motility receptor (RHAMM)



chr1_+_154298034 2.238 NM_001005855
ATP8B2
ATPase, class I, type 8B, member 2
chr1_-_205391180 2.230 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr16_+_15528324 2.227 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr5_-_19988293 2.205 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr1_+_100111430 2.157 NM_017734
PALMD
palmdelphin
chr14_+_21152735 2.130 ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr2_-_216248184 2.115 FN1
fibronectin 1
chr12_-_120315074 2.104 NM_001206999
NM_007174
CIT

citron (rho-interacting, serine/threonine kinase 21)

chrX_-_106959597 2.099 NM_001015881
TSC22D3
TSC22 domain family, member 3
chrX_+_133941204 2.091 NM_001170782
NM_001170784
NM_001170779
NM_001170781
NM_001170783
NM_138819
FAM122C





family with sequence similarity 122C





chr6_-_134498973 2.055 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr14_-_23288912 2.047 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr16_-_67700571 2.030 NM_032140
C16orf48
chromosome 16 open reading frame 48
chr7_+_100136784 2.014 NM_006076
AGFG2
ArfGAP with FG repeats 2
chr5_+_172483285 2.004 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr2_-_145274916 2.004 ZEB2
zinc finger E-box binding homeobox 2
chr6_+_159070994 1.959 NM_001009991
NM_001242384
NM_001242394
NM_001242395
SYTL3



synaptotagmin-like 3



chr2_-_74753311 1.942 NM_133637
DQX1
DEAQ box RNA-dependent ATPase 1
chrX_-_106960268 1.933 NM_004089
TSC22D3
TSC22 domain family, member 3
chr12_-_49319211 1.917 NM_001143782
NM_016594
FKBP11

FK506 binding protein 11, 19 kDa

chr12_-_121476770 1.895 NM_003733
NM_198213
OASL

2'-5'-oligoadenylate synthetase-like

chr2_+_201450579 1.887 AOX1
aldehyde oxidase 1
chr5_+_140254930 1.873 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr3_+_187086167 1.866 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr10_-_70066594 1.840 PBLD
phenazine biosynthesis-like protein domain containing
chr9_+_127420690 1.827 MIR181A2HG
MIR181A2 host gene (non-protein coding)
chr5_-_138775189 1.814 DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr4_+_86396251 1.810 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr3_+_69812620 1.807 NM_001184967
MITF
microphthalmia-associated transcription factor
chr6_+_157099262 1.798 ARID1B
AT rich interactive domain 1B (SWI1-like)
chr14_+_21156922 1.785 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr9_-_5339745 1.778 NM_006911
RLN1
relaxin 1
chr7_+_74188308 1.754 NM_000265
NCF1
NCF1B
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
chr3_+_121796695 1.746 NM_006889
NM_176892
CD86

CD86 molecule

chr15_+_42651697 1.743 NM_000070
NM_024344
NM_173087
CAPN3


calpain 3, (p94)


chr19_-_17516383 1.735 NM_004335
BST2
bone marrow stromal cell antigen 2
chr11_+_9596233 1.734 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr3_+_159557745 1.712 SCHIP1
schwannomin interacting protein 1
chr11_+_5646206 1.709 NM_021616
TRIM34
tripartite motif containing 34
chr3_+_29322802 1.708 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr2_+_11680079 1.706 NM_148903
GREB1
growth regulation by estrogen in breast cancer 1
chr1_+_24645914 1.701 NM_001195010
GRHL3
grainyhead-like 3 (Drosophila)
chr19_-_37663332 1.696 NM_199126
ZNF585A
zinc finger protein 585A
chr1_-_120935943 1.693 NM_001004340
NM_001017986
NM_001244910
FCGR1A
FCGR1B


Fc fragment of IgG, high affinity Ia, receptor (CD64)
Fc fragment of IgG, high affinity Ib, receptor (CD64)


chr13_-_30424159 1.663 UBL3
ubiquitin-like 3
chr22_+_36044475 1.654 APOL6
apolipoprotein L, 6
chr12_-_7245048 1.651 C1R
complement component 1, r subcomponent
chr11_+_65268313 1.644 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr17_+_7462064 1.642 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr6_+_132129195 1.637 ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chrM_+_3920 1.632


chr6_+_26440699 1.631 NM_001242803
NM_006994
NM_197974
BTN3A3


butyrophilin, subfamily 3, member A3


chr2_-_214015053 1.631 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr1_-_9129666 1.630 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr1_-_113161724 1.618 NM_017744
NM_138727
NM_138728
NM_138729
ST7L



suppression of tumorigenicity 7 like



chr6_+_132129154 1.603 NM_006208
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr18_+_3451589 1.600 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr6_+_43543921 1.598 POLH
polymerase (DNA directed), eta
chr20_-_25038501 1.597 NM_001252675
NM_001252677
NM_032501
ACSS1


acyl-CoA synthetase short-chain family member 1


chr1_+_87012758 1.595 NM_012128
CLCA4
chloride channel accessory 4
chr17_-_47841468 1.588 FAM117A
family with sequence similarity 117, member A
chrX_-_117251302 1.585 NM_001168301
KLHL13
kelch-like 13 (Drosophila)
chr11_+_114166534 1.578 NM_006169
NNMT
nicotinamide N-methyltransferase
chr19_+_17516502 1.569 LOC100507535
uncharacterized LOC100507535
chr4_+_187070326 1.564 NM_001006655
FAM149A
family with sequence similarity 149, member A
chrX_-_114797017 1.558


chr3_+_159557649 1.547 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr1_-_151319674 1.543 RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr1_+_79115476 1.542 NM_006417
IFI44
interferon-induced protein 44
chr2_+_152214105 1.537 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr6_+_138188352 1.522 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr6_-_133035180 1.514 NM_004666
VNN1
vanin 1
chr1_-_167487701 1.511 NM_000734
NM_198053
CD247

CD247 molecule

chr4_+_39063851 1.511 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr9_+_17134974 1.497 NM_001114395
NM_017738
CNTLN

centlein, centrosomal protein

chr21_+_47744032 1.497 NM_006031
PCNT
pericentrin
chr2_+_48807725 1.491 NM_001198594
STON1
STON1-GTF2A1L
stonin 1
STON1-GTF2A1L readthrough
chr1_-_182357757 1.480 GLUL
glutamate-ammonia ligase
chr1_+_159796506 1.474 SLAMF8
SLAM family member 8
chr1_-_161039745 1.474 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr2_+_10183630 1.470 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr12_-_10562142 1.462 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 readthrough
killer cell lectin-like receptor subfamily C, member 4
chr3_-_157221127 1.457 NM_001167911
NM_001167912
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr14_-_73493744 1.449 NM_021260
ZFYVE1
zinc finger, FYVE domain containing 1
chr12_+_510740 1.442 NM_001130146
NM_032358
CCDC77

coiled-coil domain containing 77

chr6_+_26402464 1.441 NM_001145008
NM_001145009
NM_007048
NM_194441
BTN3A1



butyrophilin, subfamily 3, member A1



chr4_-_38806410 1.434 NM_003263
TLR1
toll-like receptor 1
chr1_-_143913118 1.434 NM_207418
FAM72D
family with sequence similarity 72, member D
chr11_-_85469043 1.434 NM_001162951
NM_001162953
SYTL2

synaptotagmin-like 2

chr21_-_15918635 1.432 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr4_-_141074122 1.424 MAML3
mastermind-like 3 (Drosophila)
chr2_+_210444364 1.422 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr2_-_188419185 1.417 NM_001032281
NM_006287
TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr14_+_74003817 1.400 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr1_-_159923961 1.394 NM_001146172
NM_001146173
NM_033438
SLAMF9


SLAM family member 9


chr13_+_51915167 1.392 NM_001101320
SERPINE3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr1_+_120839004 1.385 NM_001100910
FAM72B
family with sequence similarity 72, member B
chr8_+_86019420 1.378 LRRCC1
leucine rich repeat and coiled-coil domain containing 1
chr2_-_167232464 1.375 NM_002977
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr2_-_61245363 1.369 NM_144709
PUS10
pseudouridylate synthase 10
chr12_+_51318743 1.360 METTL7A
methyltransferase like 7A
chr17_-_48546174 1.359 NM_001267
CHAD
chondroadherin
chr1_-_9129583 1.359 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr6_+_136172802 1.358 NM_018945
PDE7B
phosphodiesterase 7B
chr19_-_37663567 1.354 NM_152655
ZNF585A
zinc finger protein 585A
chr11_+_5710926 1.344 TRIM22
tripartite motif containing 22
chr2_+_237478379 1.338 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr2_+_182322265 1.337 ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr1_-_151319717 1.326 NM_000449
NM_001025603
RFX5

regulatory factor X, 5 (influences HLA class II expression)

chr12_-_57693146 1.322


chr2_-_216300444 1.321 FN1
fibronectin 1
chr11_+_63304272 1.321 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr6_+_157099203 1.320


chr4_-_70626429 1.317 NM_014465
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr13_-_30423599 1.317 UBL3
ubiquitin-like 3
chr19_-_36233311 1.307 NM_024660
IGFLR1
IGF-like family receptor 1
chr7_-_77045706 1.304 NM_017439
PION
pigeon homolog (Drosophila)
chr17_-_34207308 1.301 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr11_+_65192284 1.275 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr13_-_30424671 1.268 UBL3
ubiquitin-like 3
chr14_-_105436817 1.257 AHNAK2
AHNAK nucleoprotein 2
chr3_+_141087298 1.257 ZBTB38
zinc finger and BTB domain containing 38
chr10_+_17270469 1.257 VIM
vimentin
chr3_-_42814734 1.249 NM_144719
CCDC13
coiled-coil domain containing 13
chr8_+_37594182 1.245 NM_001003790
ERLIN2
ER lipid raft associated 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.06 9.03e-04 GO:0006955 immune response
2.49 1.20e-03 GO:0002376 immune system process
3.79 8.55e-03 GO:0045087 innate immune response
2.58 3.56e-02 GO:0006952 defense response

Nothing significant found in compartment category.

Nothing significant found in function category.